In the second experiment, fluorescein was applied topically to eight subjects to determine if each of the procedures had any effect on the amount of medication absorbed by the eye. The researchers used fluorophotometry to establish the magnitude and duration of fluorescein concentration in the anterior chamber of the eye.“Both [techniques] also show a 50% increase in maximal concentration of the drug in the eye and a 50% increase in the duration of significant concentrations of drug in the eye [in comparison with no attempt to enhance drug delivery],” Zimmerman says.
He believes that theoretically his findings apply for all topical ophthalmic drugs. That means, he says, that by using these techniques (preferably the closed-eye technique), drug solutions can be made less concentrated and still achieve the desired effects. It also means, he writes in the study, that “with these techniques, even drugs contraindicated because of systemic side effects may be used with precautions, eg, timolol with asthma or epinephrine in patients with hypertension.” Find out more about your chance to get cheap viagra pills *here at best online pharmacy.
The only problem now, Zimmerman says, is patients who ask: “But doctor how do I know when three minutes are up? My eyes are closed.”