Although less than 5% of patients taking NSAIDs experience gastrointestinal complications, such events are associated with substantial direct and indirect costs, which increase with patient age. Very cheap drugs at your disposal – diabetes drugs to get best deals at best pharmacy.
Significant excess costs are attributed to managing NSAID-associated gastrointestinal events. A recent analysis of the Quebec health insurance database (1993 to 1997) noted a higher incidence of gastrointestinal events among NSAID users than among acetaminophen users (odds ratio [OR] 2.4, 95% CI 2.1 to 3.0). The average daily direct medical costs of managing gastrointestinal events was $0.84 per day of NSAID therapy, and for each $1 spent on NSAIDs, an additional $0.66 was spent managing NSAID-related gastrointestinal side effects. A similar review of the Regie de L’assurance-Maladie du Quebec database (1993 to 1997) reported that the direct medical costs of gastrointestinal events was $1.34 per day for NSAID therapy, of which $0.94 was directly attributable to the NSAID treatment.