The pituitary content of LH in the various groups in experiments 1 and 2 is shown in Figures 1 and 2, respectively. In spring, the LH content was significantly higher in mature than in immature males (experiment 2, p < 0.001). In autumn, pituitary LH levels in sham-operated fish increased above those found in the previous spring (experiment 1 and November sampling, experiment 2; p < 0.001 in both comparisons). In experiment 2, in which fish were sampled in July, September, and November, the levels were highest in November (p < 0.001, compared to both July and September). At all samplings, the pituitary LH content was far lower in castrated than in sham-operated fish (p < 0.001 in all four comparisons); this effect was more marked in autumn than in July.
Replacement (experiment 2) with either T or 11KA increased the pituitary LH content in castrated males (p < 0.001 for T in comparison to the value in castrated males treated with empty capsules at all three samplings; p < 0.001 for 11KA in September and November, not significant in July). The effect of T was, however, far stronger than that of 11KA in this respect (p < 0.001 in all three comparisons). buy prednisone
FIG. 1. Effects of castration on pituitary LH content in male salmon parr in experiment 1. Means ± SEM for initial controls, sham-operated fish, and castrated fish are given. In some groups, means and SEM are too small to show. Number of fish is indicated on top of bars. For statistics, see Results.
FIG. 2. Effects of castration and treatment of castrated fish with T or 11KA on pituitary LH content in male salmon parr in experiment 2. Means ± SEM for mature and immature initial controls, sham-operated fish, castrated fish, and castrated fish treated with T or 11 KA are given. In some groups, means and SEM are too small to show. Number of fish is indicated on top of bars. For statistics, see Results.