Application of warm cardioplegia early in reperfusion resuscitates the ischemic rat heart (part 17)

WBCP hot shot: The first confirmation of the benefits of WBCP (ie, group 3) came from a study on the resuscitative efficiency of blood-based hot shot perfusates carried out by Rosenkranz et al . Our result of superior recovery of WBCP (group 3) compared with diluted-blood hot shot (group 2) is supported by the earlier findings . Acar et al reasoned that the noncardioplegic blood-based hot shot is accompanied by a rise in coronary vascular resistance leading to oxygen delivery deficiency.
Although the blood-based hot shot would be expected to provide superior metabolic (and functional) recovery of the heart compared with the asanguineous hot shots (group 3 versus groups 4 and 5), the similarity in recovery provided by the different cardioplegic interventions is evident from the present study. You have a great opportunity to discover the pharmacy that will always be sure to live up to your highest expectations, no matter if you would like to get Birth Control Ortho Tri Cyclen or buy any other prescription medicine with no prescription required on very advantageous terms.

Mechanical recovery of the hearts: The same two categories of groups (beating and arrested hearts) can be drawn from the hemodynamic results (Table 3). The arrested groups, groups 3 to 5, displayed better recovery than the beating groups, groups 1 and 2, in agreement with the well established correlation between the metabolic status and the mechanical functioning of the heart. On the basis of hemodynamic parameters alone, it was not possible to differentiate between the status of group 1 hearts and of group 2 hearts, with the former being perfused with KH buffer and the latter with diluted blood. Only through 31P-NMR spectroscopy studies was it possible to demonstrate clearly the added benefits provided by the blood-based solution over its crystalloid counterparts.

This entry was posted in Ischemic heart and tagged 31P-NMR spectroscopy, Blood cardioplegia, Ischemic heart.