All investitated subj ects were found to be otherwise healthy on routine examination.
Patients with idiopathic aldosteronism presented with bilateral adrenal hyperplasia on computed tomography together with a laboratory picture typical of primary aldosteronism (suppressed plasma renin activity and higher plasma aldosterone values, higher aldosterone:renin ratio, responsiveness to postural stimulation). The possibility of dexamethasone-suppressible hyperaldosteronism was excluded by dexamethasone suppression test (ie, demonstration of a marked suppression of BP and plasma aldosterone after four days’ dexamethasone [0.5 mg four times a day]).
Twenty-four hour ambulatory BP monitoring was performed using the Spacelab 90207 automated system (Spacelabs, Redmont, California, USA) . As an accuracy requirement, the paired measurement of the automated device and the reference sphygmomanometer were considered acceptable only if the difference at the beginning and at the end of 24 h BP recording did not exceed 5 mmHg. Ninety-six per cent of all readings were evaluated, and 3% of BP measurements were identified as erroneous by review of each protocol. During the BP measurements, patients were instructed to remain still and to keep the measurement arm extended in a comfortable position.
Each patient was provided with a questionnaire in order to rule out sleep disturbances. Oscillomet-ric technique was used for BP readtngs. The system was programmed for 20 min (06:00 to 22:00) and 30 min (22:00 to 06:00) interval readtngs. The lights in the patient’s room were turned off at 22:00 and patients were awaktned at 06:00. You can finally spend less time to discover discount levitra online here always paying lower prices.