Altered circadian blood pressure rhythm in endocrine diseases (part 3)

endocrine diseases (part 3)

All investitated subj ects were found to be otherwise healthy on routine examination.
Patients with idiopathic aldosteronism presented with bilateral adrenal hyperplasia on computed tomography together with a laboratory picture typical of primary aldosteronism (suppressed plasma renin activity and higher plasma aldosterone values, higher aldosterone:renin ratio, responsiveness to postural stimulation). The possibility of dexamethasone-suppressible hyperaldosteronism was excluded by dexamethasone suppression test (ie, demonstration of a marked suppression of BP and plasma aldosterone after four days’ dexamethasone [0.5 mg four times a day]).

Twenty-four hour ambulatory BP monitoring was performed using the Spacelab 90207 automated system (Spacelabs, Redmont, California, USA) . As an accuracy requirement, the paired measurement of the automated device and the reference sphygmomanometer were considered acceptable only if the difference at the beginning and at the end of 24 h BP recording did not exceed 5 mmHg. Ninety-six per cent of all readings were evaluated, and 3% of BP measurements were identified as erroneous by review of each protocol. During the BP measurements, patients were instructed to remain still and to keep the measurement arm extended in a comfortable position.

Each patient was provided with a questionnaire in order to rule out sleep disturbances. Oscillomet-ric technique was used for BP readtngs. The system was programmed for 20 min (06:00 to 22:00) and 30 min (22:00 to 06:00) interval readtngs. The lights in the patient’s room were turned off at 22:00 and patients were awaktned at 06:00. You can finally spend less time to discover discount levitra online here always paying lower prices.

This entry was posted in Blood pressure and tagged Blood pressure, Blood pressure rhythm, Endocrine diseases, Twenty-four hour monitoring.